Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09QIA
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| Former ID |
DNC009174
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| Drug Name |
9-octadecynoic acid
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| Synonyms |
Stearolic acid; 9-Octadecynoic acid; Octadec-9-ynoic acid; 506-24-1; 9-Stearolic acid; Delta(9)-octadecynoic acid; CHEMBL482804; CHEBI:28801; RGTIBVZDHOMOKC-UHFFFAOYSA-N; Stearolsaeure; Octadec-9-insaeure; EINECS 208-030-8; Octadeca-9-ynoic acid; 9-ODYA; 9-ODA; SCHEMBL196385; AC1L296J; MEGxp0_001740; AC1Q5W60; CTK1H2272; ACon1_002039; DTXSID90198647; MolPort-001-742-497; ZINC8221125; SBB069546; BDBM50292401; MFCD00014386; LMFA01030455; AKOS025117038; NCGC00179891-01; AN-45417; 9a-18:1; FT-0621682; C08459; 506S241; C-51779
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C18H32O2
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| Canonical SMILES |
CCCCCCCCC#CCCCCCCCC(=O)O
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| InChI |
1S/C18H32O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h2-8,11-17H2,1H3,(H,19,20)
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| InChIKey |
RGTIBVZDHOMOKC-UHFFFAOYSA-N
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| CAS Number |
CAS 506-24-1
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:28801
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | HMG-CoA reductase (HMGCR) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of geranylgeranyldiphosphate biosynthesis I (via mevalonate) | |||
| Superpathway of cholesterol biosynthesis | ||||
| Mevalonate pathway | ||||
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| AMPK signaling pathway | ||||
| Bile secretion | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| TSH Signaling Pathway | ||||
| Panther Pathway | Cholesterol biosynthesis | |||
| Pathwhiz Pathway | Steroid Biosynthesis | |||
| WikiPathways | Statin Pathway | |||
| Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) | ||||
| Activation of Gene Expression by SREBP (SREBF) | ||||
| SREBF and miR33 in cholesterol and lipid homeostasis | ||||
| Integrated Breast Cancer Pathway | ||||
| SREBP signalling | ||||
| Cholesterol Biosynthesis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel Acetylenic Acids from the Root Bark of Paramacrolobium caeruleum: Inhibitors of 3-Hydroxy-3-methyl-glutaryl Coenzyme A Reductase J. Nat. Prod. 52(1):153-161 (1989). | |||
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