Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09PLF
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| Former ID |
DIB014554
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| Drug Name |
Org-30029
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| Synonyms |
Org-30029; Org 30029; 101041-95-6; N'-Hydroxy-5,6-dimethoxybenzo[b]thiophene-2-carboximidamide hydrochloride; DTXSID50143698; AKOS015848621; Benzo(b)thiophene-2-carboximidamide, N-hydroxy-5,6-dimethoxy-, monohydrochloride; (Z)-N'-hydroxy-5,6-dimethoxy-1-benzothiophene-2-carboximidamide hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Heart failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9; ICD-9: 428] | Phase 2 | [1] | |
| Company |
Organon BioSciences
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| Structure |
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Download2D MOL |
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| Formula |
C11H13ClN2O3S
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| Canonical SMILES |
COC1=C(C=C2C(=C1)C=C(S2)C(=NO)N)OC.Cl
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| InChI |
1S/C11H12N2O3S.ClH/c1-15-7-3-6-4-10(11(12)13-14)17-9(6)5-8(7)16-2;/h3-5,14H,1-2H3,(H2,12,13);1H
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| InChIKey |
DVWBMWJOYIFITF-UHFFFAOYSA-N
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| CAS Number |
CAS 101041-95-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3 (PDE3) | Target Info | Modulator | [1], [2] |
| References | Top | |||
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| REF 1 | Effects of the positive inotropic agent Org 30029 on developed force and aequorin light transients in intact canine ventricular myocardium. Circ Res. 1993 Mar;72(3):597-606. | |||
| REF 2 | The presence of five cyclic nucleotide phosphodiesterase isoenzyme activities in bovine tracheal smooth muscle and the functional effects of select... Br J Pharmacol. 1991 Oct;104(2):471-7. | |||
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