Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09OTX
|
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| Former ID |
DIB004368
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| Drug Name |
RG7800
|
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| Indication | Spinal muscular atrophy [ICD-11: 8B61] | Phase 1/2 | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C24H28N6O
|
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| Canonical SMILES |
CCC1=NC(=CN2C1=CC(=N2)C3=CC(=O)N4C=C(C=C(C4=N3)C)C5CCN(CC5)C)C
|
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| InChI |
1S/C24H28N6O/c1-5-19-22-11-21(27-30(22)13-16(3)25-19)20-12-23(31)29-14-18(10-15(2)24(29)26-20)17-6-8-28(4)9-7-17/h10-14,17H,5-9H2,1-4H3
|
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| InChIKey |
GYFRQCMDLBNZSF-UHFFFAOYSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Survival motor neuron protein (SMN1) | Target Info | Modulator | [2] |
| KEGG Pathway | RNA transport | |||
| WikiPathways | Metabolism of non-coding RNA | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800039744) | |||
| REF 2 | Assays for the Identification and Prioritization of Drug Candidates for Spinal Muscular Atrophy. Assay Drug Dev Technol. 2014 August 1; 12(6): 315-341. | |||
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