Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09NNI
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| Former ID |
DNC011819
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| Drug Name |
3-Methoxy-9H-beta-carboline
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| Synonyms |
3-methoxy-9H-pyrido[3,4-b]indole; NSC627681; 91985-82-9; 9H-Pyrido[3,4-b]indole, 3-methoxy-; AC1Q4YMW; 3-Methoxy-beta-carboline; AC1L7M1C; 3-Methoxy-9H-; CHEMBL54228; CHEMBL496741; 3-Methoxy-9H-.beta.-carboline; SCHEMBL10646617; NSC-627681; 9H-.Beta.-Carbolin-3-yl methyl ether
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H10N2O
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| Canonical SMILES |
COC1=NC=C2C(=C1)C3=CC=CC=C3N2
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| InChI |
1S/C12H10N2O/c1-15-12-6-9-8-4-2-3-5-10(8)14-11(9)7-13-12/h2-7,14H,1H3
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| InChIKey |
UFGGNIMGPVLCJZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
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