Drug Information
Drug General Information | Top | |||
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Drug ID |
D09KFR
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Former ID |
DNC011085
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Drug Name |
(S)-dimethylenastron
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Synonyms |
ZINC22309237
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H18N2O2S
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Canonical SMILES |
CC1(CC2=C(C(NC(=S)N2)C3=CC(=CC=C3)O)C(=O)C1)C
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InChI |
1S/C16H18N2O2S/c1-16(2)7-11-13(12(20)8-16)14(18-15(21)17-11)9-4-3-5-10(19)6-9/h3-6,14,19H,7-8H2,1-2H3,(H2,17,18,21)/t14-/m0/s1
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InChIKey |
RUOOPLOUUAYNPY-AWEZNQCLSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Kinesin spindle messenger RNA (KIF11 mRNA) | Target Info | Inhibitor | [1] |
Reactome | MHC class II antigen presentation | |||
Kinesins | ||||
WikiPathways | MHC class II antigen presentation | |||
Kinesins |
References | Top | |||
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REF 1 | Structural basis for inhibition of Eg5 by dihydropyrimidines: stereoselectivity of antimitotic inhibitors enastron, dimethylenastron and fluorastrol. J Med Chem. 2010 Aug 12;53(15):5676-83. |
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