Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09JXM
|
|||
| Former ID |
DAP000899
|
|||
| Drug Name |
Phenylpropanolamine
|
|||
| Synonyms |
Norephedrine; phenylpropanolamine; Rhindecon; dl-Norephedrine; (+)-Norephedrine; Propagest; Dexatrim; Mucron; d-Norephedrine; Propadrine; 1r,2s-phenylpropylamine; Super Odrinex; 14838-15-4; (1S,2R)-2-amino-1-phenylpropan-1-ol; Fenilpropanolamina; dl-1-Phenyl-2-aminopropanol-1; UNII-7875H6443P; Phenylpropanolaminum; (+-)-Norephedrin; dl-Phenylpropanolamine; dl-2-Amino-1-hydroxy-1-phenylpropane; CHEBI:36; Naldecon; Cathinum [INN-Latin]; (+-)-Phenylpropanolamine; NSC9920; DLNKOYKMWOXYQA-VXNVDRBHSA-N; 37577-28-9; Cathina [INN-Spanish]; Acutrim; Cathina; Cathine; Cathinum; Codimal; Conex; Contuss; Despec; Exponcit; Fansia; Fugoa; Gentab; Guaipax; Katine; Minusine; Mydriatin; Myminic; Nolex; Norpseudoephedrine; Partuss; Phenoxine; Phenyldrine; Phenylfenesin; Phenylpropanolamina; Pseudonorephedrine; Rhymed; Snaplets; ULR; Vanex; Cathine [INN]; Fugoa Depot; Ami-Tex; D-Norpseudoephedrine; Dl-Norephedrine; Dura-Vent; Fansia (TN); L-Norephedrine; Proin (TN); Propalin (TN); Psi-Norephedrine; TAVIST-D; USAF CS-6; D-Nor-psi-ephedrine; L-Nor-psi-ephedrin; L-Nor-psi-ephedrine; D-(+)-Norephedrine; L-(-)-Norephedrine; (+-)-Norephedrine; (+/-)-Norephedrin; (+/-)-Norephedrine; (-)-Norephedrin; (-)-Norephedrine; (1R,2S)-Norephedrine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Obesity [ICD-11: 5B81; ICD-10: E66; ICD-9: 278] | Withdrawn from market | [1] | |
| Therapeutic Class |
Appetite Depressants
|
|||
| Company |
Cipla phamaceuticals
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C9H13NO
|
|||
| Canonical SMILES |
CC(C(C1=CC=CC=C1)O)N
|
|||
| InChI |
1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9-/m1/s1
|
|||
| InChIKey |
DLNKOYKMWOXYQA-VXNVDRBHSA-N
|
|||
| CAS Number |
CAS 37577-28-9
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
5392, 75272, 8137967, 8169469, 11342205, 11362388, 11372611, 11375088, 11484207, 11487790, 11488332, 11491521, 11493499, 11537926, 16214245, 24859081, 26613190, 26679282, 34669514, 46508087, 47217075, 47589250, 47662556, 47811046, 48110751, 48259528, 48334800, 48416425, 49698998, 49998290, 49998467, 50065094, 50122763, 50122764, 56365833, 57310348, 75141456, 85789326, 93166534, 104224945, 104298649, 124637421, 125309883, 126524244, 126666496, 127752080, 134338176, 134340133, 134340378, 134989328
|
|||
| ChEBI ID |
CHEBI:36
|
|||
| ADReCS Drug ID | BADD_D01764 | |||
| SuperDrug ATC ID |
R01BA01
|
|||
| SuperDrug CAS ID |
cas=014838154
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adrenergic receptor Alpha-1 (ADRA1) | Target Info | Agonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418. | |||
| REF 2 | Synthesis and structure-activity studies on N-[5-(1H-imidazol-4-yl)-5,6,7,8-tetrahydro-1-naphthalenyl]methanesulfonamide, an imidazole-containing alpha(1A)-adrenoceptor agonist. J Med Chem. 2004 Jun 3;47(12):3220-35. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.