Drug Information
Drug General Information | Top | |||
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Drug ID |
D09GJI
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Former ID |
DNC008630
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Drug Name |
7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol
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Synonyms |
CHEMBL505550; 7-(1-(1H-imidazol-1-yl)ethyl)-9H-fluoren-2-ol
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H16N2O
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Canonical SMILES |
CC(C1=CC2=C(C=C1)C3=C(C2)C=C(C=C3)O)N4C=CN=C4
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InChI |
1S/C18H16N2O/c1-12(20-7-6-19-11-20)13-2-4-17-14(8-13)9-15-10-16(21)3-5-18(15)17/h2-8,10-12,21H,9H2,1H3
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InChIKey |
LVWQDZJSHTWZHR-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] | |
BioCyc | Superpathway of steroid hormone biosynthesis | |||
Glucocorticoid biosynthesis | ||||
Mineralocorticoid biosynthesis | ||||
Androgen biosynthesis | ||||
KEGG Pathway | Steroid hormone biosynthesis | |||
Metabolic pathways | ||||
Ovarian steroidogenesis | ||||
Prolactin signaling pathway | ||||
Pathwhiz Pathway | Steroidogenesis | |||
Androgen and Estrogen Metabolism | ||||
Reactome | Glucocorticoid biosynthesis | |||
Endogenous sterols | ||||
Androgen biosynthesis | ||||
WikiPathways | Metapathway biotransformation | |||
Oxidation by Cytochrome P450 | ||||
Metabolism of steroid hormones and vitamin D | ||||
Corticotropin-releasing hormone | ||||
Steroid Biosynthesis | ||||
Glucocorticoid & Mineralcorticoid Metabolism | ||||
Prostate Cancer | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxyl... Bioorg Med Chem. 2008 Aug 15;16(16):7715-27. |
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