Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09DSZ
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| Former ID |
DNC010107
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| Drug Name |
2,3-dihydrobenzo[d]thiazole-2-thiol
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| Synonyms |
CHEMBL570797; 2,3-dihydrobenzothiazole-2-thiol; 2,3-dihydrobenzo[d]thiazole-2-thiol; 2,3-dihydro-1,3-benzothiazole-2-thiol; AC1MMT8Q; 2-benzo[d]thiazolinethiol; 2(3H)-Benzothiazolethiol; SCHEMBL1405549; BDBM50303907; AKOS006278847; 94495-79-1
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C7H7NS2
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| Canonical SMILES |
C1=CC=C2C(=C1)NC(S2)S
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| InChI |
1S/C7H7NS2/c9-7-8-5-3-1-2-4-6(5)10-7/h1-4,7-9H
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| InChIKey |
PYVUUPVBIDIYPY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation | ||||
| L-kynurenine degradation | ||||
| Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
| NAD de novo biosynthesis | ||||
| KEGG Pathway | Tryptophan metabolism | |||
| Metabolic pathways | ||||
| African trypanosomiasis | ||||
| NetPath Pathway | TSLP Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Tryptophan Metabolism | |||
| Reactome | Tryptophan catabolism | |||
| WikiPathways | Tryptophan metabolism | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem. 2010 Feb 11;53(3):1172-89. | |||
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