Drug Information
Drug General Information | Top | |||
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Drug ID |
D09DLN
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Former ID |
DNC012081
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Drug Name |
L-739749
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Synonyms |
CHEMBL99645; BDBM50059867; (S)-2-{(S)-2-[(S)-2-((R)-2-Amino-3-mercapto-propylamino)-3-methyl-pentyloxy]-3-phenyl-propionylamino}-4-methanesulfonyl-butyric acid methyl ester; (S)-methyl 2-((S)-2-((2S,3R)-2-((R)-2-amino-3-mercaptopropylamino)-3-methylpentyloxy)-3-phenylpropanamido)-4-(methylsulfonyl)butanoate
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Drug Type |
Small molecular drug
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Terminated | [1] | |
Structure |
Download2D MOL
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Formula |
C24H41N3O6S2
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Canonical SMILES |
CCC(C)C(COC(CC1=CC=CC=C1)C(=O)NC(CCS(=O)(=O)C)C(=O)OC)NCC(CS)N
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InChI |
1S/C24H41N3O6S2/c1-5-17(2)21(26-14-19(25)16-34)15-33-22(13-18-9-7-6-8-10-18)23(28)27-20(24(29)32-3)11-12-35(4,30)31/h6-10,17,19-22,26,34H,5,11-16,25H2,1-4H3,(H,27,28)/t17-,19+,20-,21+,22-/m0/s1
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InChIKey |
XDPAYLCHZOZGMW-NDYOWHOSSA-N
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CAS Number |
CAS 156511-34-1
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | CAAX farnesyltransferase beta (FNTB) | Target Info | Inhibitor | [2] |
KEGG Pathway | Terpenoid backbone biosynthesis | |||
Biosynthesis of antibiotics | ||||
NetPath Pathway | TSH Signaling Pathway | |||
Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
WikiPathways | Visual phototransduction |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800004259) | |||
REF 2 | Ras farnesyltransferase: a new therapeutic target. J Med Chem. 1997 Sep 12;40(19):2971-90. |
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