Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09CLX
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| Former ID |
DIB006973
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| Drug Name |
MDT-006
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| Synonyms |
EPX-16006; Chronic constipation, IBS-C therapy (PolyCap), MicroDose Therapeutx; P2Y2 agonist (oral, constipation/irritable bowel syndrome), EPIX; Purinoceptor P2Y2 agonist (oral, constipation/IBS), EPIX
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| Indication | Constipation [ICD-11: DD91.1; ICD-10: K59.0; ICD-9: 564] | Investigative | [1] | |
| Company |
EPIX Pharmaceuticals Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | P2Y purinoceptor 2 (P2RY2) | Target Info | Agonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL5 Signaling Pathway | |||
| Reactome | G alpha (q) signalling events | |||
| P2Y receptors | ||||
| Surfactant metabolism | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 324). | |||
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