Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09BVH
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| Former ID |
DNC010093
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| Drug Name |
Naphthalene-1,4-diol
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| Synonyms |
Naphthalene-1,4-diol; 1,4-Dihydroxynaphthalene; 571-60-8; 1,4-NAPHTHALENEDIOL; 1,4-Naphthohydroquinone; Hydronaphthoquinone; Naphthohydroquinone; 1,4-Naphthoquinol; alpha-Naphthoquinhydrone; UNII-AML1P6T42C; CCRIS 7897; Naphthalene-1,4-dio; alpha-Naphthohydroquinone; EINECS 209-336-4; BRN 1307689; AML1P6T42C; CHEMBL206816; CHEBI:34063; PCILLCXFKWDRMK-UHFFFAOYSA-N; 1,4-Naphththalenediol; 1-Hydroxy-4-naphthol; 1,4-Naphthalene diol; napthalene- 1,4-diol; ACMC-1AXHC; Naphthalenediol-(1,4); 1,4-Dihydroxy-naphthalene; AC1L1X2M
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H8O2
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CC=C2O)O
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| InChI |
1S/C10H8O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,11-12H
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| InChIKey |
PCILLCXFKWDRMK-UHFFFAOYSA-N
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| CAS Number |
CAS 571-60-8
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:34063
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation | ||||
| L-kynurenine degradation | ||||
| Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
| NAD de novo biosynthesis | ||||
| KEGG Pathway | Tryptophan metabolism | |||
| Metabolic pathways | ||||
| African trypanosomiasis | ||||
| NetPath Pathway | TSLP Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Tryptophan Metabolism | |||
| Reactome | Tryptophan catabolism | |||
| WikiPathways | Tryptophan metabolism | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem. 2010 Feb 11;53(3):1172-89. | |||
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