Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09AZO
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| Former ID |
DNC006878
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| Drug Name |
4-(3-methylpyridin-2-yl)-N-p-tolylbenzamide
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| Synonyms |
CHEMBL215015; 4-(3-methylpyridin-2-yl)-N-p-tolylbenzamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H18N2O
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| Canonical SMILES |
CC1=CC=C(C=C1)NC(=O)C2=CC=C(C=C2)C3=C(C=CC=N3)C
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| InChI |
1S/C20H18N2O/c1-14-5-11-18(12-6-14)22-20(23)17-9-7-16(8-10-17)19-15(2)4-3-13-21-19/h3-13H,1-2H3,(H,22,23)
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| InChIKey |
ACHPKRXTLZWRLG-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist. Bioorg Med Chem Lett. 2006 Oct 1;16(19):5217-21. | |||
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