Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08ZGW
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| Former ID |
DNC012960
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| Drug Name |
2-amino-2-(3-chlorophenyl)acetic acid
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| Synonyms |
7292-71-9; 2-amino-2-(3-chlorophenyl)acetic acid; Amino-(3-chloro-phenyl)-acetic acid; amino(3-chlorophenyl)acetic acid; dl-3-chlorophenylglycine; 3-chlorophenylglycine; amino-(3-chlorophenyl)acetic acid; DL-(3-Chlorophenyl)glycine; DL-2-(3-Chlorophenyl)glycine; CHEMBL204655; amino(3-chloro-phenyl)acetic acid; (R)-2-(3-Chlorophenyl)glycine; NSC154922; Benzeneacetic acid, a-amino-3-chloro-, (aS)-; PubChem20741; ACMC-20en3l; (3-chlorophenyl)glycine; AC1L6EDK; 3-Chloro-DL-phenylglycine; AC1Q3M3E; 2-(3-Chlorophenyl)glycine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H8ClNO2
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| Canonical SMILES |
C1=CC(=CC(=C1)Cl)C(C(=O)O)N
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| InChI |
1S/C8H8ClNO2/c9-6-3-1-2-5(4-6)7(10)8(11)12/h1-4,7H,10H2,(H,11,12)
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| InChIKey |
MGOUENCSVMAGSE-UHFFFAOYSA-N
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| CAS Number |
CAS 29884-14-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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