Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08XXD
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| Former ID |
DNC010092
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| Drug Name |
4-aminonaphthalen-1-ol
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| Synonyms |
4-Amino-1-naphthol; 2834-90-4; 4-Amino-1-naphthalenol; 1-Naphthalenol, 4-amino-; 1-AMINO-4-NAPHTHOL; UNII-02W29959D9; 4-amino-naphthalen-1-ol; CHEMBL576321; ABJQKDJOYSQVFX-UHFFFAOYSA-N; 4-Amino-1-naphtholhydrochloride; 02W29959D9; PCMD-CC-PAB-253; PC-0685415; 4-amino1-naphthol; 4-amino-1-naphtol; 4-azanylnaphthalen-1-ol; AC1L2AQW; 1-Amino-4-hydroxynaphthalene; SCHEMBL367092; AC1Q523Y; cid_2723858; BDBM43339; DTXSID30182580; 4-amino-1-naphthol; ZINC119431
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H9NO
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| Canonical SMILES |
C1=CC=C2C(=C1)C(=CC=C2O)N
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| InChI |
1S/C10H9NO/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6,12H,11H2
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| InChIKey |
ABJQKDJOYSQVFX-UHFFFAOYSA-N
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| CAS Number |
CAS 2834-90-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Indoleamine 2,3-dioxygenase 1 (IDO1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of tryptophan utilization | |||
| Tryptophan degradation | ||||
| L-kynurenine degradation | ||||
| Tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde | ||||
| NAD de novo biosynthesis | ||||
| KEGG Pathway | Tryptophan metabolism | |||
| Metabolic pathways | ||||
| African trypanosomiasis | ||||
| NetPath Pathway | TSLP Signaling Pathway | |||
| IL5 Signaling Pathway | ||||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Tryptophan Metabolism | |||
| Reactome | Tryptophan catabolism | |||
| WikiPathways | Tryptophan metabolism | |||
| Metabolism of amino acids and derivatives | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Rational design of indoleamine 2,3-dioxygenase inhibitors. J Med Chem. 2010 Feb 11;53(3):1172-89. | |||
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