Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08XKO
|
|||
| Former ID |
DNC004198
|
|||
| Drug Name |
8-Chloro-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
|
|||
| Synonyms |
CHEMBL98373; SCHEMBL10757832; 2H-Imidazo[4,5-b]quinolin-2-one, 8-chloro-1,3-dihydro-; BDBM50229559
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C10H6ClN3O
|
|||
| Canonical SMILES |
C1=CC2=NC3=C(C=C2C(=C1)Cl)NC(=O)N3
|
|||
| InChI |
1S/C10H6ClN3O/c11-6-2-1-3-7-5(6)4-8-9(12-7)14-10(15)13-8/h1-4H,(H2,12,13,14,15)
|
|||
| InChIKey |
VZXBGYRONYENIL-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase 3A (PDE3A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Purine metabolism | |||
| cGMP-PKG signaling pathway | ||||
| cAMP signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | cGMP effects | |||
| G alpha (s) signalling events | ||||
| WikiPathways | miR-targeted genes in muscle cell - TarBase | |||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation. J Med Chem. 1991 Sep;34(9):2906-16. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.