Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08UHS
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| Former ID |
DNC013566
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| Drug Name |
1-(1,4-diacetylphenyl)dithiosemicarbazide
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| Synonyms |
CHEMBL256865; NSC627218; AC1NTSUI; ZINC5883102; BDBM50376201; [(Z)-1-[4-[(Z)-N-(carbamothioylamino)-C-methylcarbonimidoyl]phenyl]ethylideneamino]thiourea; Hydrazinecarbothioamide, 2,2'-[1,4-phenylenedi(1Z)ethylidyne]bis-, (2Z,2'Z)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H16N6S2
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| Canonical SMILES |
CC(=NNC(=S)N)C1=CC=C(C=C1)C(=NNC(=S)N)C
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| InChI |
1S/C12H16N6S2/c1-7(15-17-11(13)19)9-3-5-10(6-4-9)8(2)16-18-12(14)20/h3-6H,1-2H3,(H3,13,17,19)(H3,14,18,20)/b15-7-,16-8-
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| InChIKey |
IFFLYNGBOLZAGJ-DUGOVBPYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102. | |||
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