Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08SZO
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| Former ID |
DIB001485
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| Drug Name |
F-12458
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| Synonyms |
CAAX tetrapeptide analogs, Pierre Fabre; Farnesyl transferase inhibitors, Pierre Fabre; Ras inhibitor, Pierre Fabre
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Investigative | [1] | |
| Company |
Pierre Fabre SA
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | CAAX farnesyltransferase beta (FNTB) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Terpenoid backbone biosynthesis | |||
| Biosynthesis of antibiotics | ||||
| NetPath Pathway | TSH Signaling Pathway | |||
| Reactome | Inactivation, recovery and regulation of the phototransduction cascade | |||
| WikiPathways | Visual phototransduction | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Recent progress in protein farnesyltransferase inhibition. IDrugs. 2000 Nov;3(11):1336-45. | |||
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