Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08SPJ
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| Former ID |
DNC003862
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| Drug Name |
3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4aH)-one
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| Synonyms |
CHEMBL99448; 3,4,5,6-Tetrahydrobenzo[c]quinolizin-3-(4aH)-one; SCHEMBL6940070; LNTWPSKEEYNUKK-UHFFFAOYSA-N; BDBM50072192; 4,4a,5,6-Tetrahydro-pyrido[1,2-a]quinolin-3-one; 4,4a,5,6-Tetrahydro-3H-benzo[c]quinolizine-3-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H13NO
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| Canonical SMILES |
C1CC2=CC=CC=C2N3C1CC(=O)C=C3
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| InChI |
1S/C13H13NO/c15-12-7-8-14-11(9-12)6-5-10-3-1-2-4-13(10)14/h1-4,7-8,11H,5-6,9H2
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| InChIKey |
LNTWPSKEEYNUKK-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 5-alpha-reductase 1 (SRD5A1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Allopregnanolone biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | Androgen biosynthesis | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Benzo[c]quinolizin-3-ones: a novel class of potent and selective nonsteroidal inhibitors of human steroid 5alpha-reductase 1. J Med Chem. 2000 Oct 5;43(20):3718-35. | |||
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