Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08PXF
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| Drug Name |
Aminopyrimidine derivative 1
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| Synonyms |
PMID25656651-Compound-12a
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| Drug Type |
Small molecular drug
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| Company |
VERTEX PHARMACEUTICALS INCORPORATED
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H34N8OS
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| Canonical SMILES |
CCC(=O)NC1=CC=C(C=C1)SC2=NC(=CC(=N2)N3CCC4(CCN(C4)C)CC3)NC5=NNC(=C5)C
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| InChI |
1S/C26H34N8OS/c1-4-24(35)27-19-5-7-20(8-6-19)36-25-29-21(28-22-15-18(2)31-32-22)16-23(30-25)34-13-10-26(11-14-34)9-12-33(3)17-26/h5-8,15-16H,4,9-14,17H2,1-3H3,(H,27,35)(H2,28,29,30,31,32)
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| InChIKey |
ODMCGDLIMBCHLX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl (Bcr-Abl) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fusion protein Bcr-Abl (Bcr-Abl) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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