Drug Information
Drug General Information | Top | |||
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Drug ID |
D08OSM
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Former ID |
DNC006467
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Drug Name |
3-(furan-3-yl)-1H-indole
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Synonyms |
CHEMBL381132; 155440-58-7; 3-(3-furyl)indole; 3-(furan-3-yl)-1H-indole; 3-(3-Furanyl)-1H-indole; BDBM50182886
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C12H9NO
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Canonical SMILES |
C1=CC=C2C(=C1)C(=CN2)C3=COC=C3
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InChI |
1S/C12H9NO/c1-2-4-12-10(3-1)11(7-13-12)9-5-6-14-8-9/h1-8,13H
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InChIKey |
AFKNGDFJVAPDNN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Inosine-5'-monophosphate dehydrogenase 2 (IMPDH2) | Target Info | Inhibitor | [1] |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Guanosine nucleotides de novo biosynthesis | ||||
Superpathway of purine nucleotide salvage | ||||
Purine nucleotides de novo biosynthesis | ||||
Guanosine ribonucleotides de novo biosynthesis | ||||
KEGG Pathway | Purine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Panther Pathway | De novo purine biosynthesis | |||
Reactome | Purine ribonucleoside monophosphate biosynthesis |
References | Top | |||
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REF 1 | Low molecular weight indole fragments as IMPDH inhibitors. Bioorg Med Chem Lett. 2006 May 1;16(9):2535-8. |
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