Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08OHU
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| Former ID |
DNC013093
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| Drug Name |
1-(3,5-bis(trifluoromethyl)benzyl)-1H-imidazole
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| Synonyms |
CHEMBL213596; 1-(3,5-bis(trifluoromethyl)benzyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C12H8F6N2
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| Canonical SMILES |
C1=CN(C=N1)CC2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F
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| InChI |
1S/C12H8F6N2/c13-11(14,15)9-3-8(6-20-2-1-19-7-20)4-10(5-9)12(16,17)18/h1-5,7H,6H2
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| InChIKey |
XITLEILYHLIBPC-UHFFFAOYSA-N
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| CAS Number |
CAS 906478-70-4
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 17-alpha-monooxygenase (S17AH) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Androgen biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| Prolactin signaling pathway | ||||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Steroidogenesis | ||||
| Reactome | Androgen biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Steroid Biosynthesis | ||||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Glucocorticoid & Mineralcorticoid Metabolism | ||||
| Prostate Cancer | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hy... Bioorg Med Chem Lett. 2006 Aug 1;16(15):4011-5. | |||
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