Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08OFD
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| Former ID |
DNC013572
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| Drug Name |
1-(1-p-tolylethylidene)thiosemicarbazide
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| Synonyms |
CHEMBL256866; 7410-54-0; NSC8380; AC1NS5IF; DTXSID70417787; MolPort-020-322-439; ZINC502706; 1-p-Tolylethanone thiosemicarbazone; NSC-8380; BDBM50376198; AKOS002388601; AKOS008939485
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C10H13N3S
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| Canonical SMILES |
CC1=CC=C(C=C1)C(=NNC(=S)N)C
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| InChI |
1S/C10H13N3S/c1-7-3-5-9(6-4-7)8(2)12-13-10(11)14/h3-6H,1-2H3,(H3,11,13,14)/b12-8-
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| InChIKey |
CLXMWTWYQLEKAI-WQLSENKSSA-N
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| CAS Number |
CAS 7410-54-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-(1-Arylethylidene)thiosemicarbazide derivatives: a new class of tyrosinase inhibitors. Bioorg Med Chem. 2008 Feb 1;16(3):1096-102. | |||
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