Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08NES
|
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| Former ID |
DIB004957
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| Drug Name |
S-3536
|
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| Indication | Osteoarthritis [ICD-11: FA00-FA05; ICD-9: 715] | Discontinued in Phase 1 | [1] | |
| Company |
Shionogi & Co Ltd
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C10H9NO
|
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| Canonical SMILES |
COC1=CC2=C(C=C1)C=NC=C2
|
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| InChI |
1S/C10H9NO/c1-12-10-3-2-9-7-11-5-4-8(9)6-10/h2-7H,1H3
|
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| InChIKey |
XZNUJESLPUNSNO-UHFFFAOYSA-N
|
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| CAS Number |
CAS 52986-70-6
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Matrix metalloproteinase (MMP) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800019710) | |||
| REF 2 | CIINE Reflects Collagenase-Specific CII Breakdown in Cartilage Explant and Whole Body of Canine. Biomark Insights. 2013; 8: 77-83. | |||
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