Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08MVV
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| Former ID |
DIB006259
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| Drug Name |
PRX-111
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| Synonyms |
FSH variants (female infertility), Protalix Biotherapeutics/ Compugen; Follicle stimulating hormone variants (female infertility), Protalix Biotherapeutics/ Compugen
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| Indication | Female infertility [ICD-11: GA31.Z; ICD-9: 628] | Investigative | [1] | |
| Company |
Protalix BioTherapeutics Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Follicle-stimulating hormone receptor (FSHR) | Target Info | Modulator | [2] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Ovarian steroidogenesis | ||||
| Pathwhiz Pathway | Vasopressin Regulation of Water Homeostasis | |||
| Intracellular Signalling Through FSH Receptor and Follicle Stimulating Hormone | ||||
| Reactome | Hormone ligand-binding receptors | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Ovarian Infertility Genes | ||||
| Peptide GPCRs | ||||
| FSH signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028182) | |||
| REF 2 | A naturally occurring basically charged human follicle-stimulating hormone (FSH) variant inhibits FSH-induced androgen aromatization and tissue-type plasminogen activator enzyme activity in vitro. Neuroendocrinology. 1998 Mar;67(3):153-63. | |||
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