Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08MUX
|
|||
| Former ID |
DNC002363
|
|||
| Drug Name |
S33005
|
|||
| Synonyms |
S33005; SCHEMBL945666; BDBM85805; PDSP2_000811; PDSP1_000824
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Depression [ICD-11: 6A70-6A7Z; ICD-9: 311] | Investigative | [1] | |
| Therapeutic Class |
Psychiatric
|
|||
| Company |
Servier
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C18H27NO2
|
|||
| Canonical SMILES |
CN(C)CC1(CC2=C1C=C(C=C2)OC)C3(CCCCC3)O
|
|||
| InChI |
1S/C18H27NO2/c1-19(2)13-17(18(20)9-5-4-6-10-18)12-14-7-8-15(21-3)11-16(14)17/h7-8,11,20H,4-6,9-10,12-13H2,1-3H3
|
|||
| InChIKey |
UBIQMAFTTDZGEX-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 242473-59-2
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Norepinephrine transporter (NET) | Target Info | Inhibitor | [1] |
| Serotonin transporter (SERT) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Serotonergic synapse | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
| 5HT2 type receptor mediated signaling pathway | ||||
| 5HT3 type receptor mediated signaling pathway | ||||
| 5HT4 type receptor mediated signaling pathway | ||||
| Adrenaline and noradrenaline biosynthesis | ||||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| SIDS Susceptibility Pathways | ||||
| NRF2 pathway | ||||
| Synaptic Vesicle Pathway | ||||
| Serotonin Transporter Activity | ||||
| Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Serotonin reuptake inhibitors: the corner stone in treatment of depression for half a century--a medicinal chemistry survey. Curr Top Med Chem. 2006;6(17):1801-23. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.