Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08JUW
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| Former ID |
DNC003008
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| Drug Name |
PCNOTAXIME GROUP
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| Synonyms |
open; hydrolyzed; C3'-cleaved; (2r)-2-[(R)-{[(2z)-2-(2-Amino-1,3-Thiazol-4-Yl)-2-(Methoxyimino)acetyl]amino}(Carboxy)methyl]-5-Methylidene-5,6-Dihydro-2h-1,3-Thiazine-4-Carboxylic Acid; AC1O43RR; (2R)-2-[(R)-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido](carboxy)methyl]-5-methylidene-2,6-dihydro-1,3-thiazine-4-carboxylic acid; (2R)-2-[(1R)-1-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-2-hydroxy-2-oxoethyl]-5-methylidene-2H-1,3-thiazine-4-carboxylic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H15N5O6S2
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| Canonical SMILES |
CON=C(C1=CSC(=N1)N)C(=O)NC(C2N=C(C(=C)CS2)C(=O)O)C(=O)O
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| InChI |
1S/C14H15N5O6S2/c1-5-3-26-11(18-7(5)12(21)22)9(13(23)24)17-10(20)8(19-25-2)6-4-27-14(15)16-6/h4,9,11H,1,3H2,2H3,(H2,15,16)(H,17,20)(H,21,22)(H,23,24)/b19-8+/t9-,11+/m0/s1
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| InChIKey |
ZRDXEERHKBZJMY-VGMFVZOQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Penicillin binding protein 3 (Bact mrcA) | Target Info | Inhibitor | [1] |
| Staphylococcus Beta-lactamase (Stap-coc blaZ) | Target Info | Inhibitor | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42. | |||
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