Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08JMZ
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| Drug Name |
PMID25522065-Compound-5
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| Drug Type |
Small molecular drug
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| Company |
ALBANY MOLECULAR RESEARCH, INC
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| Structure |
 |
Download2D MOL |
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| Formula |
C25H23FN4O2
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| Canonical SMILES |
CN1C2=C(C3CCC(C2)N3)C4=C1C=C(C=C4)N5C=CC(=CC5=O)OCC6=NC=C(C=C6)F
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| InChI |
1S/C25H23FN4O2/c1-29-22-11-18(5-6-20(22)25-21-7-4-16(28-21)10-23(25)29)30-9-8-19(12-24(30)31)32-14-17-3-2-15(26)13-27-17/h2-3,5-6,8-9,11-13,16,21,28H,4,7,10,14H2,1H3
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| InChIKey |
WIHBSZQMVJUBGL-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Antagonist | [1] |
| Target's Patent Info | Melanin-concentrating hormone receptor 1 (MCHR1) | Target's Patent Info | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel MCH1 receptor antagonists: a patent review.Expert Opin Ther Pat. 2015 Feb;25(2):193-207. | |||
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