Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08IDB
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| Former ID |
DIB012063
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| Drug Name |
HuA33
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| Synonyms |
CDP-833; A33-radionuclides, American Cyanamid; A33-radionuclides, Celltech; HuA33, Ludwig Institute for Cancer Research/Life Science Pharmaceuticals
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| Drug Type |
Antibody
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| Indication | Colorectal cancer [ICD-11: 2B91.Z] | Phase 1 | [1], [2] | |
| Company |
UCB Celltech
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cell surface A33 antigen (GPA33) | Target Info | . | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00199797) Phase I Trial of huA33 Plus Chemotherapy in Patients With Metastatic Colorectal Cancer. U.S. National Institutes of Health. | |||
| REF 2 | Phase I trial of 131I-huA33 in patients with advanced colorectal carcinoma. Clin Cancer Res. 2005 Jul 1;11(13):4818-26. | |||
| REF 3 | (124)I-huA33 antibody PET of colorectal cancer. J Nucl Med. 2011 Aug;52(8):1173-80. | |||
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