Drug Information
Drug General Information | Top | |||
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Drug ID |
D08HOK
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Former ID |
DIB019471
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Drug Name |
PMID21444206C3a
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Synonyms |
GTPL5737; BDBM50343447; 142831-EP2292620A2; 142831-EP2287165A2; 142831-EP2287166A2
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] | |
Structure |
Download2D MOL
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Formula |
C22H27N5O5S
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Canonical SMILES |
CC(C)(C)OC(=O)N1CCC(CC1)OC2=NC=NC3=C2C=NN3C4=CC=C(C=C4)S(=O)(=O)C
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InChI |
1S/C22H27N5O5S/c1-22(2,3)32-21(28)26-11-9-16(10-12-26)31-20-18-13-25-27(19(18)23-14-24-20)15-5-7-17(8-6-15)33(4,29)30/h5-8,13-14,16H,9-12H2,1-4H3
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InChIKey |
LZCNLEZPKDPKSO-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Glucose-dependent insulinotropic receptor (GPR119) | Target Info | Agonist | [1] |
KEGG Pathway | cAMP signaling pathway | |||
Insulin secretion | ||||
WikiPathways | Incretin Synthesis, Secretion, and Inactivation |
References | Top | |||
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REF 1 | Discovery of fused bicyclic agonists of the orphan G-protein coupled receptor GPR119 with in vivo activity in rodent models of glucose control. Bioorg Med Chem Lett. 2011 May 15;21(10):3134-41. | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5737). |
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