Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08HHA
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| Former ID |
DNC010495
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| Drug Name |
1-(3-Fluorobenzyl)-1H-imidazole
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| Synonyms |
1-(3-Fluorobenzyl)-1H-imidazole; 109485-43-0; 1H-Imidazole, 1-[(3-fluorophenyl)methyl]-; CHEMBL598390; ACMC-20mcbr; 1-(3-Fluorobenzyl)imidazole; N-(3-fluorobenzyl)-imidazole; SCHEMBL9747422; CTK0D5768; DTXSID10601148; CJNXVRZKOSWWND-UHFFFAOYSA-N; BDBM50307214; ZINC41391477; AKOS009098433
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C10H9FN2
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| Canonical SMILES |
C1=CC(=CC(=C1)F)CN2C=CN=C2
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| InChI |
1S/C10H9FN2/c11-10-3-1-2-9(6-10)7-13-5-4-12-8-13/h1-6,8H,7H2
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| InChIKey |
CJNXVRZKOSWWND-UHFFFAOYSA-N
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| CAS Number |
CAS 109485-43-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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