Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08FZT
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| Former ID |
DIB009951
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| Drug Name |
Corus 1030
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| Synonyms |
Inhaled Lidocaine
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Discontinued in Phase 2 | [1] | |
| Company |
Gilead Sciences
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.7 (SCN9A) | Target Info | Modulator | [2], [3] |
| Voltage-gated sodium channel alpha Nav1.8 (SCN10A) | Target Info | Modulator | [2], [3] | |
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800017745) | |||
| REF 2 | Differential modulation of Nav1.7 and Nav1.8 peripheral nerve sodium channels by the local anesthetic lidocaine. Br J Pharmacol. 2004 Jun;142(3):576-84. | |||
| REF 3 | Lidocaine reduces the transition to slow inactivation in Na(v)1.7 voltage-gated sodium channels.Br J Pharmacol.2011 Sep;164(2b):719-30. | |||
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