Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08FOX
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| Former ID |
DIB007894
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| Drug Name |
Piroximone
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| Synonyms |
MDL-19205
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| Drug Type |
Small molecular drug
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| Indication | Cardiac failure [ICD-11: BD10-BD13; ICD-10: I50, I50.9] | Discontinued in Phase 3 | [1] | |
| Company |
Hoechst Marion Roussel Inc
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| Structure |
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Download2D MOL |
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| Formula |
C11H11N3O2
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| Canonical SMILES |
CCC1=C(NC(=O)N1)C(=O)C2=CC=NC=C2
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| InChI |
1S/C11H11N3O2/c1-2-8-9(14-11(16)13-8)10(15)7-3-5-12-6-4-7/h3-6H,2H2,1H3,(H2,13,14,16)
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| InChIKey |
OQGWJZOWLHWFME-UHFFFAOYSA-N
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| CAS Number |
CAS 84490-12-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphodiesterase (PDE) | Target Info | Inhibitor | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000260) | |||
| REF 2 | Circulatory effects of the PDE-inhibitors piroximone and enoximone. Br J Clin Pharmacol. 1993 Oct;36(4):309-14. | |||
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