Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08DWG
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| Drug Name |
Phenylpyridine derivative 1
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| Synonyms |
PMID26161698-Compound-40
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| Drug Type |
Small molecular drug
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| Company |
NOVARTIS AG PFISTER, Keith B SENDZIK, Martin
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H29ClN4O2
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| Canonical SMILES |
C1CC(CNC1)C(=O)NC2=NC=C(C(=C2)C3=CC(=CC=C3)NCC4CCOCC4)Cl
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| InChI |
1S/C23H29ClN4O2/c24-21-15-27-22(28-23(29)18-4-2-8-25-14-18)12-20(21)17-3-1-5-19(11-17)26-13-16-6-9-30-10-7-16/h1,3,5,11-12,15-16,18,25-26H,2,4,6-10,13-14H2,(H,27,28,29)
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| InChIKey |
UUPXZCDRKZMXRB-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cyclin-dependent kinase 9 (CDK9) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Cyclin-dependent kinase 9 (CDK9) | Target's Patent Info | [1] | |
| KEGG Pathway | Transcriptional misregulation in cancer | |||
| NetPath Pathway | EGFR1 Signaling Pathway | |||
| Reactome | SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription | |||
| WikiPathways | Cardiac Hypertrophic Response | |||
| Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer | ||||
| Host Interactions of HIV factors | ||||
| HIV Life Cycle | ||||
| IL-9 Signaling Pathway | ||||
| RNA Polymerase II Transcription | ||||
| MicroRNAs in cardiomyocyte hypertrophy | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cyclin-dependent kinase inhibitors for cancer therapy: a patent review (2009 - 2014).Expert Opin Ther Pat. 2015;25(9):953-70. | |||
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