Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08DMH
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| Drug Name |
BAY2402234
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| Synonyms |
KNVJMHHAXCPZHF-JTQLQIEISA-N; BAY-2402234; SCHEMBL20108031; HY-112645; CS-0058850
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| Indication | Myeloid leukaemia [ICD-11: 2B33.1; ICD-9: 208.9] | Phase 1 | [1] | |
| Company |
Bayer Pharmaceuticals Whippany, NJ
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| Structure |
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Download2D MOL |
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| Formula |
C21H18ClF5N4O4
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| Canonical SMILES |
CCN1C(=NN(C1=O)C2=C(C=C(C(=C2)OC(C)C(F)(F)F)C(=O)NC3=C(C=CC=C3Cl)F)F)CO
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| InChI |
1S/C21H18ClF5N4O4/c1-3-30-17(9-32)29-31(20(30)34)15-8-16(35-10(2)21(25,26)27)11(7-14(15)24)19(33)28-18-12(22)5-4-6-13(18)23/h4-8,10,32H,3,9H2,1-2H3,(H,28,33)/t10-/m0/s1
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| InChIKey |
KNVJMHHAXCPZHF-JTQLQIEISA-N
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| CAS Number |
CAS 2225819-06-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dihydroorotate dehydrogenase (DHODH) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Pyrimidine metabolism | |||
| Metabolic pathways | ||||
| Panther Pathway | De novo pyrimidine ribonucleotides biosythesis | |||
| Pathwhiz Pathway | Pyrimidine Metabolism | |||
| Reactome | Pyrimidine biosynthesis | |||
| WikiPathways | Metabolism of nucleotides | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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