Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08CDE
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| Former ID |
DCL000082
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| Drug Name |
Celgosivir
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| Synonyms |
BuCast; MDL 28574; B-CAST; MBI-3253; MDL 28,574; MDL 28,574A; MDL-28574; MX-3253; VIR-222; Butanoic acid, (1S,6S,7S,8R,8aR)-octahydro-1,7,8-trihydroxy-6-indolizinyl ester; [(1S,6S,7S,8R,8aR)-1,7,8-trihydroxy-1,2,3,5,6,7,8,8a-octahydroindolizin-6-yl] butanoate; (1S,6S,7S,8R,8aR)-Octahydro-1,7,8-trihydroxy-6-indolizinyl butyrate;6-O-Butanoylcastanospermine
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| Drug Type |
Small molecular drug
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| Indication | Dengue fever [ICD-11: 1D2Z; ICD-10: A97, A97.9; ICD-9: 61] | Phase 1/2 | [1] | |
| Company |
Migenix
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| Structure |
 |
Download2D MOL |
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| Formula |
C12H21NO5
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| Canonical SMILES |
CCCC(=O)OC1CN2CCC(C2C(C1O)O)O
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| InChI |
1S/C12H21NO5/c1-2-3-9(15)18-8-6-13-5-4-7(14)10(13)12(17)11(8)16/h7-8,10-12,14,16-17H,2-6H2,1H3/t7-,8-,10+,11+,12+/m0/s1
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| InChIKey |
HTJGLYIJVSDQAE-VWNXEWBOSA-N
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| CAS Number |
CAS 121104-96-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Intestinal maltase-glucoamylase (MGAM) | Target Info | Modulator | [2] |
| KEGG Pathway | Galactose metabolism | |||
| Starch and sucrose metabolism | ||||
| Metabolic pathways | ||||
| Carbohydrate digestion and absorption | ||||
| Pathwhiz Pathway | Starch and Sucrose Metabolism | |||
| WikiPathways | Metabolism of carbohydrates | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003977) | |||
| REF 2 | Celgosivir, an alpha-glucosidase I inhibitor for the potential treatment of HCV infection.Curr Opin Investig Drugs.2009 Aug;10(8):860-70. | |||
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