Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BLM
|
|||
| Former ID |
DNC010222
|
|||
| Drug Name |
9-benzyl-6-(4-methylpiperazin-1-yl)-9H-purine
|
|||
| Synonyms |
CHEMBL594468; 9-benzyl-6-(4-methylpiperazin-1-yl)-9H-purine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C17H20N6
|
|||
| Canonical SMILES |
CN1CCN(CC1)C2=NC=NC3=C2N=CN3CC4=CC=CC=C4
|
|||
| InChI |
1S/C17H20N6/c1-21-7-9-22(10-8-21)16-15-17(19-12-18-16)23(13-20-15)11-14-5-3-2-4-6-14/h2-6,12-13H,7-11H2,1H3
|
|||
| InChIKey |
JSSGUCJSJQMEEQ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H4 receptor (H4R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 2,4-Diaminopyrimidines as histamine H4 receptor ligands--Scaffold optimization and pharmacological characterization. Bioorg Med Chem. 2009 Oct 15;17(20):7186-96. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.