Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07YSJ
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| Former ID |
DNC014557
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| Drug Name |
(3-Amino-1-ethyl-propyl)-methyl-phosphinic acid
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| Synonyms |
CHEMBL113092; 133345-70-7; Phosphinic acid, (3-amino-1-ethylpropyl)methyl-; ACMC-20muwd; (3-Amino-1-ethyl-propyl)-methyl-phosphinic acid; SCHEMBL341182; CTK0C0402; DTXSID30435583; CCGFQGUALPHBIC-UHFFFAOYSA-N; BDBM50032974; P-(5-aminopent-3-yl)-P-methylphosphinic acid; P-(5-aminopent-3-yl)-P-methyl-phosphinic acid; Phosphinic acid, P-(3-amino-1-ethylpropyl)-P-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C6H16NO2P
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| Canonical SMILES |
CCC(CCN)P(=O)(C)O
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| InChI |
1S/C6H16NO2P/c1-3-6(4-5-7)10(2,8)9/h6H,3-5,7H2,1-2H3,(H,8,9)
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| InChIKey |
CCGFQGUALPHBIC-UHFFFAOYSA-N
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| CAS Number |
CAS 133345-70-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Gamma-aminobutyric acid B receptor (GABBR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | cAMP signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| GABAergic synapse | ||||
| Estrogen signaling pathway | ||||
| Morphine addiction | ||||
| Reactome | Activation of G protein gated Potassium channels | |||
| G alpha (i) signalling events | ||||
| Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
| Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits | ||||
| WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Potassium Channels | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Phosphinic acid analogues of GABA. 1. New potent and selective GABAB agonists. J Med Chem. 1995 Aug 18;38(17):3297-312. | |||
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