Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07VWP
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| Former ID |
DNC001262
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| Drug Name |
S-9947
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| Synonyms |
S9947; CHEMBL148159; AC1LCVHN; CHEBI:34965; 2'-(Benzyloxycarbonylaminomethyl)biphenyl-2-carboxylic acid 2-(2-pyridyl)ethylamide; SureCN498662; S-9947; SCHEMBL498662; GTPL2562; FLOLVFLAXFXKBU-UHFFFAOYSA-N; MolPort-042-665-732; CHEBI:342860; ZINC1491423; BDBM50123508; NCGC00386602-01; C13771; benzyl N-[[2-[2-(2-pyridin-2-ylethylcarbamoyl)phenyl]phenyl]methyl]carbamate; benzyl N-[[2-[2-[2-(2-pyridyl)ethylcarbamoyl]phenyl]phenyl]methyl]carbamate; [2''-(2-Pyridin-2-yl-ethylcarbamoyl)-biphenyl-2-ylmethyl]-carbamic acid benzyl este
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| Drug Type |
Small molecular drug
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| Indication | Atrial fibrillation [ICD-11: BC81.3; ICD-10: I48] | Investigative | [1] | |
| Company |
Aventis
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H27N3O3
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| Canonical SMILES |
C1=CC=C(C=C1)COC(=O)NCC2=CC=CC=C2C3=CC=CC=C3C(=O)NCCC4=CC=CC=N4
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| InChI |
1S/C29H27N3O3/c33-28(31-19-17-24-13-8-9-18-30-24)27-16-7-6-15-26(27)25-14-5-4-12-23(25)20-32-29(34)35-21-22-10-2-1-3-11-22/h1-16,18H,17,19-21H2,(H,31,33)(H,32,34)
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| InChIKey |
FLOLVFLAXFXKBU-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:34965
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv1.5 (KCNA5) | Target Info | Blocker | [2] |
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Voltage gated Potassium channels | |||
| WikiPathways | Potassium Channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2562). | |||
| REF 2 | New antiarrhythmic agents for atrial fibrillation and atrial flutter. Expert Opin Emerg Drugs. 2005 May;10(2):311-22. | |||
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