Drug Information
Drug General Information | Top | |||
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Drug ID |
D07VNH
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Drug Name |
Acebilustat
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Synonyms |
UNII-J64RI4D29U; J64RI4D29U; 943764-99-6; Acebilustat [INN]; Acebilustat(ZK322); Acebilustat [WHO-DD]; SCHEMBL3036353; MolPort-046-033-585; EX-A1277; EP-501; AKOS030632028; CS-5999; HY-17625; Benzoic acid, 4-(((1S,4S)-5-((4-(4-(2-oxazolyl)phenoxy)phenyl)methyl)-2,5-diazabicyclo(2.2.1)hept-2-yl)methyl)-
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Indication | Chronic blistering skin disorder [ICD-11: ME63.3] | Phase 1 | [1] | |
Company |
Celtaxsys Atlanta, GA
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Structure |
Download2D MOL |
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Formula |
C29H27N3O4
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Canonical SMILES |
C1C2CN(C1CN2CC3=CC=C(C=C3)OC4=CC=C(C=C4)C5=NC=CO5)CC6=CC=C(C=C6)C(=O)O
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InChI |
1S/C29H27N3O4/c33-29(34)23-5-1-20(2-6-23)16-31-18-25-15-24(31)19-32(25)17-21-3-9-26(10-4-21)36-27-11-7-22(8-12-27)28-30-13-14-35-28/h1-14,24-25H,15-19H2,(H,33,34)/t24-,25-/m0/s1
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InChIKey |
GERJIEKMNDGSCS-DQEYMECFSA-N
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CAS Number |
CAS 943764-99-6
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Leukotriene A-4 hydrolase (LTA4H) | Target Info | Inhibitor | [1] |
BioCyc | Leukotriene biosynthesis | |||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Arachidonic acid metabolism | |||
Eicosanoid Synthesis |
References | Top | |||
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REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) |
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