Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07UNH
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| Drug Name |
Pyridine and pyrimidine derivative 1
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| Synonyms |
PMID28447479-Compound-1
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| Drug Type |
Small molecular drug
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| Indication | Fibrosis [ICD-11: GA14-GC01] | Patented | [1] | |
| Pain [ICD-11: MG30-MG3Z] | Patented | [1] | ||
| Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Patented | [1] | ||
| Company |
INHIBITAXIN LIMITED
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| Structure |
 |
Download2D MOL |
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| Formula |
C24H21FN4OS
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| Canonical SMILES |
C1CN(CC2=C1N=CN=C2CC3=CC=C(C=C3)F)C(=O)CCC4=NC5=CC=CC=C5S4
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| InChI |
1S/C24H21FN4OS/c25-17-7-5-16(6-8-17)13-21-18-14-29(12-11-19(18)26-15-27-21)24(30)10-9-23-28-20-3-1-2-4-22(20)31-23/h1-8,15H,9-14H2
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| InChIKey |
JGNVAVQZDSOAGO-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Extracellular lysophospholipase D (E-NPP2) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Extracellular lysophospholipase D (E-NPP2) | Target's Patent Info | [1] | |
| KEGG Pathway | Ether lipid metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Autotaxin inhibitors: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):815-829. | |||
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