Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07RXX
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| Former ID |
DIB008374
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| Drug Name |
HG-1051
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| Synonyms |
CD136 modulator (inflammation/immune disorders), Human Genome Sciences; CD137 antigen modulator (inflammation/immune disorders), Human Genome Sciences; CDw137 modulator (inflammation/immune disorders), Human Genome Sciences; Homolog of mouse Ly63 modulator (inflammation/immune disorders), Human Genome Sciences; ILA modulator (inflammation/immune disorders), Human Genome Sciences; MGC2172 modulator (inflammation/immune disorders), Human Genome Sciences; T cell antigen ILA modulator (inflammation/immune disorders), Human Genome Sciences; TNFRSF9 modulator (inflammation/immune disorders), Human Genome Sciences; Tumor necrosis factor receptor superfamily member 9 modulator (inflammation/immune disorders), Human Genome Sciences; Homolog of mouse 4-1BB modulator (inflammation/immune disorders), Human Genome Sciences; Human 4-1BB receptor splicing varifant modulator (inflammation/immune disorders), Human Genome Sciences; Induced by lymphocyte activation (ILA) modulator (inflammation/immune disorders), Human Genome Sciences; Interleukin-activated receptor modulator (inflammation/immune disorders), Human Genome Sciences; 4-1BB ligand receptor modulator (inflammation/immune disorders), Human Genome Sciences; 4-1BB modulator (inflammation/immune disorders), Human Genome Sciences
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| Indication | Immune System disease [ICD-11: 4A01-4B41; ICD-10: D80-D89] | Investigative | [1] | |
| Company |
Human Genome Sciences Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Co-stimulatory molecule 4-1BB (CD137) | Target Info | Modulator | [1] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| NetPath Pathway | TCR Signaling Pathway | |||
| Pathway Interaction Database | Downstream signaling in naï | |||
| WikiPathways | TCR Signaling Pathway | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1878). | |||
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