Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07QGX
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| Former ID |
DNC012956
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| Drug Name |
2-amino-2-(2,4-difluorophenyl)acetic acid
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| Synonyms |
2-amino-2-(2,4-difluorophenyl)acetic Acid; 240409-02-3; 2,4-DIFLUORO-DL-PHENYLGLYCINE; amino(2,4-difluorophenyl)acetic acid; CHEMBL382622; Amino-(2,4-difluoro-phenyl)-acetic acid; alpha-Amino-2,4-difluorobenzeneacetic acid; AC1MC6PH; SCHEMBL1115280; CTK7I4174; DTXSID70371799; MolPort-000-165-848; COIWYFIMAXMSKX-UHFFFAOYSA-N; AC1Q5058; KS-00003QV7; BDBM50179695; SBB090539; AKOS016051288; AKOS000170674; PS-6697; QC-3701; AB11996; RP03495; SC-59456; FT-0691426; BB 0249675; 2-aMino-2-(2;4-difluorophenyl)acetic acid; Y8397; EN300-88022
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H7F2NO2
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| Canonical SMILES |
C1=CC(=C(C=C1F)F)C(C(=O)O)N
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| InChI |
1S/C8H7F2NO2/c9-4-1-2-5(6(10)3-4)7(11)8(12)13/h1-3,7H,11H2,(H,12,13)
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| InChIKey |
COIWYFIMAXMSKX-UHFFFAOYSA-N
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| CAS Number |
CAS 240409-02-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated calcium channel alpha-2/delta-1 (CACNA2D1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | MAPK signaling pathway | |||
| Cardiac muscle contraction | ||||
| Adrenergic signaling in cardiomyocytes | ||||
| Oxytocin signaling pathway | ||||
| Hypertrophic cardiomyopathy (HCM) | ||||
| Arrhythmogenic right ventricular cardiomyopathy (ARVC) | ||||
| Dilated cardiomyopathy | ||||
| Panther Pathway | Muscarinic acetylcholine receptor 2 and 4 signaling pathway | |||
| WikiPathways | Arrhythmogenic Right Ventricular Cardiomyopathy | |||
| miR-targeted genes in muscle cell - TarBase | ||||
| miR-targeted genes in lymphocytes - TarBase | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1138-41. | |||
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