Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07PNM
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| Former ID |
DIB020337
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| Drug Name |
methyl isocyanate
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| Synonyms |
isocyanatomethane; methyl carbonimide; isocyanic acid
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C2H3NO
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| Canonical SMILES |
CN=C=O
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| InChI |
1S/C2H3NO/c1-3-2-4/h1H3
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| InChIKey |
HAMGRBXTJNITHG-UHFFFAOYSA-N
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| CAS Number |
CAS 624-83-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
110287, 589868, 3155087, 7643139, 8159109, 10530597, 14793619, 17388916, 29280474, 48417653, 48421615, 48423680, 48425294, 49855636, 51075236, 52893694, 53788884, 57327467, 57568205, 57642282, 88829103, 92741967, 104328392, 119507770, 124406518, 124890416, 125570785, 126689675, 127326169, 127326170, 127326171, 127326172, 127326173, 127326174, 127795881, 127828353, 128032755, 131321534, 131498543, 134977521, 135158899, 135584707, 137001545, 142045549, 142291579, 144208258, 152137114, 160999230, 162238955, 162630919
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| ChEBI ID |
CHEBI:59059
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transformation-sensitive protein p120 (TRPA1) | Target Info | Activator | [2] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6290). | |||
| REF 2 | Transient receptor potential ankyrin 1 antagonists block the noxious effects of toxic industrial isocyanates and tear gases. FASEB J. 2009 Apr;23(4):1102-14. | |||
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