Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07PBZ
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| Former ID |
DAP000202
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| Drug Name |
Epoetin alfa
|
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| Synonyms |
Epogen (TN); Procrit (TN)
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|
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| Indication | Anemia [ICD-11: 3A00-3A9Z; ICD-9: 280-285] | Approved | [1] | |
| Therapeutic Class |
Antianemic Agents
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| Company |
Amgen Inc
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| ADReCS Drug ID | BADD_D00787 | |||
| SuperDrug ATC ID |
B03XA01
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Erythropoietin Receptor (EPOR) | Target Info | Agonist | [2], [3] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| PI3K-Akt signaling pathway | ||||
| Jak-STAT signaling pathway | ||||
| Hematopoietic cell lineage | ||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | |||
| Pathway Interaction Database | Signaling events mediated by Stem cell factor receptor (c-Kit) | |||
| EPO signaling pathway | ||||
| WikiPathways | EPO Receptor Signaling | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (BLA) 103951. | |||
| REF 2 | 2007 Standards, Options, and Recommendations: use of erythropoiesis-stimulating agents (ESA: epoetin alfa, epoetin beta, and darbepoetin) for the management of anemia in children with cancer. PediatrBlood Cancer. 2009 Jul;53(1):7-12. | |||
| REF 3 | Knockouts model the 100 best-selling drugs--will they model the next 100 Nat Rev Drug Discov. 2003 Jan;2(1):38-51. | |||
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