Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07OSS
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| Former ID |
DIB006592
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| Drug Name |
9cUAB-30
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| Synonyms |
UAB-112; UAB-20; UAB-30; UAB-75; UAB-76; UAB-8; Retinoic acid analogs (cancer), University of Alabama; (9Z)-UAB-30
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Phase 1 | [1] | |
| Company |
University of Alabama at Birmingham
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Retinoic acid receptor RXR-gamma (RXRG) | Target Info | Modulator | [1] |
| KEGG Pathway | PPAR signaling pathway | |||
| Thyroid hormone signaling pathway | ||||
| Adipocytokine signaling pathway | ||||
| Pathways in cancer | ||||
| Transcriptional misregulation in cancer | ||||
| Thyroid cancer | ||||
| Small cell lung cancer | ||||
| Non-small cell lung cancer | ||||
| Pathway Interaction Database | Regulation of Androgen receptor activity | |||
| RXR and RAR heterodimerization with other nuclear receptor | ||||
| Retinoic acid receptors-mediated signaling | ||||
| a6b1 and a6b4 Integrin signaling | ||||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Adipogenesis | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | In vitro metabolic characterization, phenotyping, and kinetic studies of 9cUAB30, a retinoid X receptor-specific retinoid. Drug Metab Dispos. 2007 Jul;35(7):1157-64. | |||
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