Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07MXF
|
|||
| Former ID |
DIB016789
|
|||
| Drug Name |
Zabofloxacin
|
|||
| Synonyms |
DW-224a; DW-224aa; PB-101; Zabofloxacin (oral), IASO Pharma/DHP
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Pneumonia [ICD-11: CA40] | Phase 3 | [1] | |
| Company |
Dong Wha Pharmaceutical Co Ltd
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C19H20FN5O4
|
|||
| Canonical SMILES |
CON=C1CN(CC12CNC2)C3=C(C=C4C(=O)C(=CN(C4=N3)C5CC5)C(=O)O)F
|
|||
| InChI |
1S/C19H20FN5O4/c1-29-23-14-6-24(9-19(14)7-21-8-19)17-13(20)4-11-15(26)12(18(27)28)5-25(10-2-3-10)16(11)22-17/h4-5,10,21H,2-3,6-9H2,1H3,(H,27,28)/b23-14+
|
|||
| InChIKey |
ZNPOCLHDJCAZAH-OEAKJJBVSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial DNA gyrase (Bact gyrase) | Target Info | Modulator | [2] |
| Staphylococcus Topoisomerase IV (Stap-coc parC) | Target Info | Modulator | [2] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01658020) A Study to Evaluate Efficacy and Safety Profile of Zabofloxacin Tablet 400mg and Moxifloxacin Tablet 400mg. U.S. National Institutes of Health. | |||
| REF 2 | DNA gyrase and topoisomerase IV are dual targets of zabofloxacin in Streptococcus pneumoniae.Int J Antimicrob Agents.2010 Jul;36(1):97-8. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.