Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07MRF
|
|||
| Former ID |
DNC012344
|
|||
| Drug Name |
3-Nitro-9H-beta-carboline
|
|||
| Synonyms |
9H-Pyrido[3,4-b]indole, 3-nitro-; AC1NFSZR; 3-Nitro-beta-carboline; CHEMBL53229; CHEMBL487006; 3-nitro-9H-pyrido[3,4-b]indole
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C11H7N3O2
|
|||
| Canonical SMILES |
C1=CC=C2C(=C1)C3=CC(=NC=C3N2)[N+](=O)[O-]
|
|||
| InChI |
1S/C11H7N3O2/c15-14(16)11-5-8-7-3-1-2-4-9(7)13-10(8)6-12-11/h1-6,13H
|
|||
| InChIKey |
XQNOYQREYCKAIN-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore. J Med Chem. 1988 Sep;31(9):1854-61. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.