Drug Information
Drug General Information | Top | |||
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Drug ID |
D07LBQ
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Former ID |
DIB002845
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Drug Name |
GSK2398852
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Synonyms |
2398852
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Drug Type |
Antibody
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Indication | Amyloidosis [ICD-11: 5D00; ICD-9: 277.3] | Phase 1 | [1], [2] |
Target and Pathway | Top | |||
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Target(s) | Serum amyloid P-component (APCS) | Target Info | . | [2], [3] |
Reactome | Amyloid formation | |||
WikiPathways | Human Complement System | |||
Amyloids |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8255). | |||
REF 2 | ClinicalTrials.gov (NCT01777243) A Study to Evaluate the Safety of GSK2398852 When Co-administered With GSK2315698 in Patients With Systemic Amyloidosis. U.S. National Institutes of Health. | |||
REF 3 | PRM-151 (recombinant human serum amyloid P/pentraxin 2) for the treatment of fibrosis. Drug News Perspect. 2010 Jun;23(5):305-15. |
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