Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07KXZ
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| Former ID |
DNC014395
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| Drug Name |
5-phenyl-1,3,4-oxadiazole-2(3H)-thione
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| Synonyms |
3004-42-0; 5-Phenyl-1,3,4-oxadiazole-2-thiol; 5-Phenyl-1,3,4-oxadiazole-2(3H)-thione; 1,3,4-Oxadiazole-2(3H)-thione, 5-phenyl-; 2-Phenyl-1,3,4-oxadiazole-5-thiol; 1,3,4-oxadiazole-2-thiol, 5-phenyl-; EINECS 221-103-9; 5-Phenyl-[1,3,4]oxadiazole-2-thiol; 2-Fenil-5-mercapto-1,3,4-ossadiazolo; CHEMBL1164316; 1,3,4-OXADIAZOLE-5-THIOL, 2-PHENYL-; FOHWXVBZGSVUGO-UHFFFAOYSA-N; 2-Fenil-5-mercapto-1,3,4-ossadiazolo [Italian]; 5-phenyl-1,3,4-oxadiazole-2-thione; 2-Phenyl-1,3,4--oxadiazol-5-thiol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H6N2OS
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| Canonical SMILES |
C1=CC=C(C=C1)C2=NNC(=S)O2
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| InChI |
1S/C8H6N2OS/c12-8-10-9-7(11-8)6-4-2-1-3-5-6/h1-5H,(H,10,12)
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| InChIKey |
FOHWXVBZGSVUGO-UHFFFAOYSA-N
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| CAS Number |
CAS 3004-42-0
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Tyrosinase (TYR) | Target Info | Inhibitor | [1] |
| BioCyc | (S)-reticuline biosynthesis | |||
| Eumelanin biosynthesis | ||||
| L-dopachrome biosynthesis | ||||
| KEGG Pathway | Tyrosine metabolism | |||
| Riboflavin metabolism | ||||
| Metabolic pathways | ||||
| Melanogenesis | ||||
| Pathwhiz Pathway | Riboflavin Metabolism | |||
| Tyrosine Metabolism | ||||
| WikiPathways | Dopamine metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2(3H)-thiones, 1,3,4-oxadiazole-2(3H)-thiones, 4-amino-1,2,4-triaz... Bioorg Med Chem. 2010 Jun 1;18(11):4042-8. | |||
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