Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07KTA
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| Former ID |
DIB001849
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| Drug Name |
Ab-01
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| Synonyms |
Ab-02; IL-21 receptor-targeted human monoclonal antibodies (inflammation); Anti-IL-21R mAb (inflammation), Pfizer; IL-21 receptor-targeted human monoclonal antibodies (inflammation), Pfizer
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| Drug Type |
Antibody
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| Indication | Inflammation [ICD-11: 1A00-CA43.1] | Phase 2 | [1] | |
| Company |
Pfizer Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Interleukin 21 receptor (IL21R) | Target Info | . | [2] |
| KEGG Pathway | Cytokine-cytokine receptor interaction | |||
| Jak-STAT signaling pathway | ||||
| Inflammatory bowel disease (IBD) | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| IL5 Signaling Pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00447837) Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitis. U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2304). | |||
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